SCARF2

Across TCGA cell cohorts, SCARF2 mutation is significantly associated with the RNA expression of many other genes, with 532 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCARF2-associated genes across cancer lineages are GPR101, OR56A1, and IZUMO1R. Each is linked with SCARF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCARF2-to-partner and partner-to-SCARF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by SCARF2-low versus SCARF2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARF2→partner) and Y-score (partner→SCARF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPR101 →	+0.128	+4.551	<.001	.004	3	2
UPPER_AERODIGESTIVE_TRACT	OR56A1 →	+0.059	+4.736	<.001	.009	3	2
BLOOD_Leukemia	IZUMO1R →	+0.118	+4.539	<.001	.007	3	2
UPPER_AERODIGESTIVE_TRACT	GK2 →	+0.115	+4.736	<.001	.009	3	2
URINARY_TRACT	C16orf90 →	+0.023	+5.087	<.001	.004	3	1
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

GPR101 by SCARF2 expression — BLOOD_Leukemia

Explore this box plot interactively →