SCARF1

Across TCGA patient cohorts, SCARF1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,983 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCARF1-associated genes across cancer lineages are CCRL2, PDE1B, and SH2D3C. Each is linked with SCARF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCARF1-to-partner and partner-to-SCARF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCARF1 versus CCRL2 in LSCC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARF1→partner) and Y-score (partner→SCARF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCRL2 →	+0.764	+0.346	<.001	<.001	3	5
GBM	PDE1B →	+0.439	+0.560	.005	.005	3	5
LSCC	SH2D3C →	+0.598	+0.322	<.001	<.001	3	5
LSCC	CD69 →	+0.953	+0.316	<.001	<.001	3	4
LSCC	FCGR2A →	+0.764	+0.310	<.001	<.001	3	4
LSCC	FCER1G →	+0.831	+0.336	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,983 associations by consensus.

SCARF1 vs CCRL2 — LSCC

Explore this scatter interactively →