SCARF1

Across TCGA cell cohorts, SCARF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,799 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCARF1-associated GO terms across cancer lineages are Establishment of protein localization to vacuole, Protein targeting to lysosome, and Positive regulation of axon regeneration. Each is linked with SCARF1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SCARF1-to-partner and partner-to-SCARF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to vacuole grouped by SCARF1-low versus SCARF1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARF1→partner) and Y-score (partner→SCARF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.063	+0.320	.005	.001	2	9
SOFT_TISSUE	Protein targeting to lysosome →	+0.081	+0.937	<.001	.004	3	8
BLOOD_Lymphoma	Positive regulation of axon regeneration →	-0.136	-0.773	<.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of neuron projection regeneration →	-0.136	-0.773	<.001	<.001	3	8
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.055	+0.426	.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Protein localization to plasma membrane →	+0.074	+0.309	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,799 associations by consensus.

Establishment of protein localization to vacuole by SCARF1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →