SCARF1

Across TCGA cell cohorts, SCARF1 mutation is significantly associated with the drug of many other genes, with 37 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCARF1-associated genes across cancer lineages are Bleomycin (10 uM), Luminespib, and AZD5582. Each is linked with SCARF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCARF1-to-partner and partner-to-SCARF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bleomycin (10 uM) grouped by SCARF1-low versus SCARF1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARF1→partner) and Y-score (partner→SCARF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Bleomycin (10 uM) →	+0.642	+2.169	.001	.046	3	2
LARGE_INTESTINE	Luminespib →	+0.584	+2.868	.043	.022	3	1
LARGE_INTESTINE	AZD5582 →	+0.631	+2.868	.022	.022	3	1
LARGE_INTESTINE	GSK1070916 →	+0.820	+2.655	.005	.044	3	1
BLOOD_Leukemia	AZD8055 →	-0.320	-2.807	.040	.044	3	1
BLOOD_Leukemia	Oxaliplatin →	-0.369	-2.669	.018	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Bleomycin (10 uM) by SCARF1 expression — BLOOD_Leukemia

Explore this box plot interactively →