SCARB2

Across TCGA patient cohorts, SCARB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,445 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SCARB2-associated proteins across cancer lineages are ILK, WDFY3, and SEPTIN11. Each is linked with SCARB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCARB2-to-partner and partner-to-SCARB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCARB2 versus ILK in BRCA, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARB2→partner) and Y-score (partner→SCARB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ILK →	+0.355	+0.498	<.001	.001	3	5
LSCC	WDFY3 →	+0.204	+0.416	.002	.003	3	5
OV	SEPTIN11 →	+0.459	+0.743	<.001	<.001	3	5
BRCA	ITGAV →	+0.531	+0.517	<.001	<.001	3	5
OV	ITGB5 →	+0.658	+0.518	<.001	<.001	3	5
UCEC	GBA →	+0.449	+0.610	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,445 associations by consensus.

SCARB2 vs ILK — BRCA

Explore this scatter interactively →