SCARA5

Across TCGA patient cohorts, SCARA5 mutation is significantly associated with the RNA expression of many other genes, with 1,961 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCARA5-associated genes across cancer lineages are FMO4, POMT1, and NDOR1. Each is linked with SCARA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCARA5-to-partner and partner-to-SCARA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FMO4 grouped by SCARA5-low versus SCARA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARA5→partner) and Y-score (partner→SCARA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FMO4 →	-0.578	-3.874	<.001	<.001	3	3
UCEC	POMT1 →	+0.469	+3.169	<.001	<.001	3	3
UCEC	NDOR1 →	+0.457	+2.807	.002	.003	3	3
LIHC	MIR6846 →	+0.498	+5.676	<.001	.001	3	2
UCEC	BAG3 →	+0.721	+2.502	<.001	.002	3	2
UCEC	SAR1B →	+0.488	+2.346	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,961 associations by consensus.

FMO4 by SCARA5 expression — UCEC

Explore this box plot interactively →