SCARA3

Across TCGA cell cohorts, SCARA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,631 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SCARA3-associated GO terms across cancer lineages are Negative regulation of complement-dependent cytotoxicity, Negative regulation of activation of membrane attack complex, and Immune complex clearance. Each is linked with SCARA3 in more than 16 cancer types. Because this analysis shows association rather than direction, both SCARA3-to-partner and partner-to-SCARA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of complement-dependent cytotoxicity grouped by SCARA3-low versus SCARA3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARA3→partner) and Y-score (partner→SCARA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of complement-dependent cytotoxicity →	+0.318	+2.750	<.001	<.001	3	17
LARGE_INTESTINE	Negative regulation of activation of membrane attack complex →	+0.288	+2.652	<.001	<.001	3	16
SKIN	Immune complex clearance →	+0.952	+1.900	<.001	<.001	3	16
OVARY	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.197	+3.365	<.001	<.001	3	15
STOMACH	Chaperone-mediated autophagy →	+0.200	+3.304	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of inclusion body assembly →	+0.249	+3.668	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,631 associations by consensus.

Negative regulation of complement-dependent cytotoxicity by SCARA3 expression — LARGE_INTESTINE

Explore this box plot interactively →