SCARA3

Across TCGA cell cohorts, SCARA3 mutation is significantly associated with the RNA expression of many other genes, with 260 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCARA3-associated genes across cancer lineages are PHF5A, POLR3H, and SGK2. Each is linked with SCARA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCARA3-to-partner and partner-to-SCARA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHF5A grouped by SCARA3-low versus SCARA3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARA3→partner) and Y-score (partner→SCARA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PHF5A →	+0.530	+3.628	.001	<.001	3	1
LARGE_INTESTINE	POLR3H →	+0.699	+3.169	.002	.006	3	1
LARGE_INTESTINE	SGK2 →	-1.623	-3.169	.003	.009	3	1
LARGE_INTESTINE	ADNP2 →	+0.653	+3.169	.004	.009	3	1
LARGE_INTESTINE	ERI1 →	+0.758	+2.502	<.001	.005	3	1
LARGE_INTESTINE	MTMR9 →	+0.594	+2.502	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 260 associations by consensus.

PHF5A by SCARA3 expression — LARGE_INTESTINE

Explore this box plot interactively →