SCAND1

Across TCGA pan-cancer cohorts, SCAND1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SCAND1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SCAND1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SCAND1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, HNSC, and STAD are the cancer types where SCAND1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SCAND1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.850	<.001	9	view →
HNSC	Male	III,IV	+0.884	<.001	8	view →
STAD	All	II,III,IV	+0.701	<.001	8	view →
LIHC	All	II,III,IV	+0.727	<.001	7	view →
KICH	All	II,III,IV	−0.687	<.001	7	view →
BRCA	All	III,IV	+0.756	<.001	6	view →
LUSC	All	All	+0.368	.003	4	view →
KIRC	All	III,IV	+0.323	.013	4	view →
CHOL	Male	All	+0.991	<.001	2	view →
ESCA	All	All	+0.977	<.001	2	view →
UCEC	All	All	+0.453	.040	2	view →
KIRP	All	II,III,IV	+0.444	.033	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SCAND1–COAD

Open the COAD breakdown →