Across TCGA pan-cancer cohorts, SCAMP5 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SCAMP5 data layer compared with 19 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SCAMP5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SCAMP5 expression acts as an unfavorable survival marker.

LUSC, UCEC, and HNSC are the cancer types where SCAMP5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.178	0.776	.003	30	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
HNSC	DFS	Median	All	0.208	0.695	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SCAMP5 tumor-vs-normal RNA expression · all SCAMP5 data types