Across TCGA patient cohorts, SCAMP5 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAMP5-associated genes across cancer lineages are eIF4E, 14-3-3_beta, and EGFR. Each is linked with SCAMP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCAMP5-to-partner and partner-to-SCAMP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAMP5→partner) and Y-score (partner→SCAMP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	eIF4E →	+0.271	+3.321	.003	.010	3	2
UCEC	14-3-3_beta →	-0.160	-2.986	<.001	.001	3	1
UCEC	EGFR →	-0.197	-1.807	.002	.027	3	1
UCEC	FOXO3a_pS318_S321 →	-0.113	-2.449	.027	.019	3	1
UCEC	G6PD →	-0.323	-2.564	.015	.010	3	1
UCEC	Heregulin →	-0.113	-1.807	.027	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

SCAMP5 survival (RNA) · tumor vs normal (RNA) · all SCAMP5 data types