Across TCGA patient cohorts, SCAMP4 mutation is significantly associated with the RNA expression of many other genes, with 476 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAMP4-associated genes across cancer lineages are RNU6-1151P, RPL7L1P4, and MTCO2P8. Each is linked with SCAMP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCAMP4-to-partner and partner-to-SCAMP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAMP4→partner) and Y-score (partner→SCAMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1151P →	+0.358	+3.356	<.001	.005	3	2
COAD	RPL7L1P4 →	+0.215	+5.080	<.001	.008	3	2
CESC	MTCO2P8 →	+0.067	+5.418	.001	.005	3	1
CESC	MIR4662B →	+0.441	+5.539	<.001	.004	3	1
UCEC	LINC01943 →	+0.657	+3.354	<.001	.005	3	1
UCEC	PACSIN2 →	+0.743	+3.191	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 476 associations by consensus.

Exploration

SCAMP4 survival (RNA) · tumor vs normal (RNA) · all SCAMP4 data types