SCAMP1

Across TCGA pan-cancer cohorts, SCAMP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SCAMP1 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SCAMP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SCAMP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and COAD show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where SCAMP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.936	0.679	.004	23	view →
LSCC	DFS	Tertile	All	0.382	1.000	.001	12	view →
LUAD	DFS	Median	II,III,IV	0.776	0.930	.015	10	view →
COAD	DFS	Median	III,IV	1.000	0.844	.044	6	view →
CCRCC	DFS	Median	All	0.518	0.898	.012	6	view →
PDAC	DFS	Quartile	All	0.706	0.961	.007	3	view →
GBM	DFS	Median	All	0.822	0.674	.015	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SCAMP1–HNSC (DFS)

Open the HNSC breakdown →