Across TCGA patient cohorts, SCAF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,976 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCAF8-associated proteins across cancer lineages are SMC3, HDAC2, and SCAF8_S617. Each is linked with SCAF8 in more than 6 cancer types. Because this analysis shows association rather than direction, both SCAF8-to-partner and partner-to-SCAF8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF8→partner) and Y-score (partner→SCAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC3 →	+0.321	+0.357	.003	.006	3	7
GBM	HDAC2 →	+0.292	+0.352	<.001	<.001	3	7
GBM	SCAF8_S617 →	+0.429	+0.464	<.001	<.001	3	6
LUAD	AFDN →	+0.304	+0.391	<.001	<.001	3	6
LSCC	GATAD2B →	+0.344	+0.569	<.001	<.001	3	6
GBM	NONO →	+0.234	+0.415	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,976 associations by consensus.

Exploration

SCAF8 survival (RNA) · tumor vs normal (RNA) · all SCAF8 data types