Across TCGA patient cohorts, SCAF8 protein abundance is significantly associated with the RNA expression of many other genes, with 13,059 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCAF8-associated genes across cancer lineages are PDCD2, HBS1L, and TCP1. Each is linked with SCAF8 in more than 7 cancer types. Because this analysis shows association rather than direction, both SCAF8-to-partner and partner-to-SCAF8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF8→partner) and Y-score (partner→SCAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PDCD2 →	+0.452	+0.175	<.001	<.001	3	8
LSCC	HBS1L →	+0.492	+0.152	<.001	<.001	3	7
LSCC	TCP1 →	+0.591	+0.210	<.001	<.001	3	7
HNSC	ORC3 →	+0.543	+0.216	.007	<.001	3	7
BRCA	VTA1 →	+0.504	+0.205	<.001	<.001	3	7
BRCA	PHF10 →	+0.638	+0.272	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,059 associations by consensus.

Exploration

SCAF8 survival (RNA) · tumor vs normal (RNA) · all SCAF8 data types