SCAF8

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SCAF8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,572 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCAF8-associated GO terms across cancer lineages are Regulation of termination of RNA polymerase II transcription, Regulation of termination of DNA-templated transcription, and Termination of RNA polymerase II transcription. Each is linked with SCAF8 in more than 19 cancer types. Because this analysis shows association rather than direction, both SCAF8-to-partner and partner-to-SCAF8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF8→partner) and Y-score (partner→SCAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRegulation of termination of RNA polymerase II transcription →+0.148+0.659<.001<.001320
STOMACHRegulation of termination of DNA-templated transcription →+0.148+0.659<.001<.001320
KIDNEYTermination of RNA polymerase II transcription →+0.139+1.117<.001<.001320
OESOPHAGUSRegulation of termination of RNA polymerase II transcription, poly(A)-coupled →+0.143+0.555<.001.002220
SOFT_TISSUERNA polymerase I preinitiation complex assembly →+0.139+0.707<.001<.001317
BLOOD_MyelomaNegative regulation of ubiquitin protein ligase activity →+0.194+1.117<.001<.001317
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,572 associations by consensus.

Exploration