SCAF4

Across TCGA patient cohorts, SCAF4 mutation is significantly associated with the RNA expression of many other genes, with 5,324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAF4-associated genes across cancer lineages are RNA5SP271, BOLA3, and GRPEL2. Each is linked with SCAF4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCAF4-to-partner and partner-to-SCAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP271 grouped by SCAF4-low versus SCAF4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF4→partner) and Y-score (partner→SCAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP271 →	+0.608	+5.044	.001	.009	3	4
UCEC	BOLA3 →	+0.254	+1.578	.004	.002	3	4
UCEC	GRPEL2 →	+0.371	+1.704	<.001	<.001	3	4
STAD	GSR →	+0.794	+3.203	<.001	.009	3	4
UCEC	PARP2 →	+0.400	+1.584	<.001	<.001	3	4
UCEC	TXNL4A →	+0.281	+2.042	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,324 associations by consensus.

RNA5SP271 by SCAF4 expression — LUAD

Explore this box plot interactively →