SCAF11

Across TCGA cell cohorts, SCAF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,108 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SCAF11-associated GO terms across cancer lineages are Protein sumoylation, Protein deubiquitination, and Nuclear transport. Each is linked with SCAF11 in more than 16 cancer types. Because this analysis shows association rather than direction, both SCAF11-to-partner and partner-to-SCAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sumoylation grouped by SCAF11-low versus SCAF11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF11→partner) and Y-score (partner→SCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein sumoylation →	+0.068	+0.795	<.001	.002	3	17
LUNG_NSCLC_LUSC	Protein deubiquitination →	+0.056	+0.638	.002	.003	3	15
SOFT_TISSUE	Nuclear transport →	+0.073	+0.726	<.001	.003	3	15
BONE	Regulation of centrosome cycle →	+0.119	+0.992	<.001	<.001	3	14
BLOOD_Lymphoma	RNA destabilization →	+0.058	+0.955	<.001	<.001	3	14
BONE	Regulation of centrosome duplication →	+0.111	+0.947	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,108 associations by consensus.

Protein sumoylation by SCAF11 expression — BONE

Explore this box plot interactively →