SCAF11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SCAF11 protein abundance is significantly associated with the RNA expression of many other genes, with 3,499 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCAF11-associated genes across cancer lineages are PRKD2, DHRS2, and IRF2BP2. Each is linked with SCAF11 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCAF11-to-partner and partner-to-SCAF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCAF11 versus PRKD2 in BLOOD_Myeloma, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF11→partner) and Y-score (partner→SCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaPRKD2 →+1.977+1.985<.001.00435
CNSDHRS2 →+2.803+1.191.002<.00134
CNSIRF2BP2 →-0.691-0.895.001.00734
UPPER_AERODIGESTIVE_TRACTHLA-C →+3.081+1.135.001.00234
BREASTCST6 →+3.640+0.976.002.00533
KIDNEYTMEM17 →-0.853-0.601.001.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,499 associations by consensus.

SCAF11 vs PRKD2 — BLOOD_Myeloma

Per-sample scatter of SCAF11 vs PRKD2 in BLOOD_Myeloma (Pearson r = 0.82).

Explore this scatter interactively →

Exploration