SCAF11

Across TCGA cell cohorts, SCAF11 mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCAF11-associated genes across cancer lineages are IL1F10, IFNL2, and DPRX. Each is linked with SCAF11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCAF11-to-partner and partner-to-SCAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL1F10 grouped by SCAF11-low versus SCAF11-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF11→partner) and Y-score (partner→SCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IL1F10 →	+0.224	+4.369	<.001	.008	3	2
SOFT_TISSUE	IFNL2 →	+0.080	+4.635	<.001	.003	3	2
SOFT_TISSUE	DPRX →	+0.049	+4.369	<.001	.008	3	2
SOFT_TISSUE	FOXR1 →	+0.142	+4.222	<.001	.007	3	1
OESOPHAGUS	SLC10A2 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

IL1F10 by SCAF11 expression — SOFT_TISSUE

Explore this box plot interactively →