SCAF1

Across TCGA patient cohorts, SCAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,617 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCAF1-associated genes across cancer lineages are CXCR2, PTOV1, and TFDP2. Each is linked with SCAF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SCAF1-to-partner and partner-to-SCAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCAF1 versus CXCR2 in LSCC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF1→partner) and Y-score (partner→SCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CXCR2 →	-1.027	-0.209	<.001	<.001	3	6
GBM	PTOV1 →	+0.435	+0.188	<.001	<.001	3	5
LSCC	TFDP2 →	+0.541	+0.243	<.001	<.001	3	5
HNSC	CEP68 →	+0.509	+0.199	.002	.001	3	5
GBM	MCM3AP-AS1 →	+0.482	+0.234	<.001	<.001	3	5
BRCA	G0S2 →	-1.707	-0.288	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,617 associations by consensus.

SCAF1 vs CXCR2 — LSCC

Explore this scatter interactively →