SCAF1

Across TCGA cell cohorts, SCAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,527 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCAF1-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Endosomal transport, and mRNA alternative polyadenylation. Each is linked with SCAF1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SCAF1-to-partner and partner-to-SCAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by SCAF1-low versus SCAF1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF1→partner) and Y-score (partner→SCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.086	+0.648	<.001	.008	3	18
STOMACH	Endosomal transport →	+0.088	+1.290	<.001	<.001	3	17
KIDNEY	mRNA alternative polyadenylation →	+0.082	+0.782	.007	.008	3	16
BONE	Nucleic acid transport →	+0.094	+0.902	.005	.005	3	16
BONE	RNA transport →	+0.094	+0.902	.005	.005	3	16
STOMACH	Protein stabilization →	+0.078	+1.089	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,527 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by SCAF1 expression — BREAST

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