SCAF1

Across TCGA cell cohorts, SCAF1 mutation is significantly associated with the RNA expression of many other genes, with 1,891 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCAF1-associated genes across cancer lineages are C2orf42, RBBP4, and MTRNR2L6. Each is linked with SCAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCAF1-to-partner and partner-to-SCAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2orf42 grouped by SCAF1-low versus SCAF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF1→partner) and Y-score (partner→SCAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C2orf42 →	+0.422	+2.339	.002	.009	3	3
LARGE_INTESTINE	RBBP4 →	+0.566	+1.721	.001	.003	3	3
UPPER_AERODIGESTIVE_TRACT	MTRNR2L6 →	+0.130	+4.357	<.001	.006	3	3
LARGE_INTESTINE	CEP97 →	+0.456	+2.179	.004	.001	3	3
LARGE_INTESTINE	NIPSNAP1 →	+0.618	+2.700	.003	.001	3	3
LARGE_INTESTINE	ATP2A1 →	+0.753	+2.130	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,891 associations by consensus.

C2orf42 by SCAF1 expression — LARGE_INTESTINE

Explore this box plot interactively →