SBSPON

Across TCGA patient cohorts, SBSPON RNA expression is significantly associated with the protein abundance of many other proteins, with 11,901 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SBSPON-associated proteins across cancer lineages are RPL7, ZNF703_S252, and STXBP1. Each is linked with SBSPON in more than 3 cancer types. Because this analysis shows association rather than direction, both SBSPON-to-partner and partner-to-SBSPON results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SBSPON versus RPL7 in GBM, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSPON→partner) and Y-score (partner→SBSPON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.334	-0.712	.001	.001	3	4
LSCC	ZNF703_S252 →	+1.000	+1.141	<.001	.002	3	4
UCEC	STXBP1 →	+0.574	+1.285	<.001	.001	3	4
HNSC	ITPKB →	+0.429	+1.129	<.001	<.001	3	4
UCEC	MACROH2A2 →	+0.754	+1.513	<.001	<.001	3	4
LSCC	POGZ →	+0.298	+1.069	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,901 associations by consensus.

SBSPON vs RPL7 — GBM

Explore this scatter interactively →