SBSPON

Across TCGA patient cohorts, SBSPON mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SBSPON-associated genes across cancer lineages are Platelets, CD8+ Tem, and pDC. Each is linked with SBSPON in more than 1 cancer types. Because this analysis shows association rather than direction, both SBSPON-to-partner and partner-to-SBSPON results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by SBSPON-low versus SBSPON-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSPON→partner) and Y-score (partner→SBSPON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Platelets →	+0.052	+4.121	<.001	.028	3	2
UCEC	CD8+ Tem →	+0.004	+4.896	<.001	.036	3	1
UCEC	pDC →	+0.060	+3.008	.024	.019	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by SBSPON expression — CESC

Explore this box plot interactively →