SBSPON

Across TCGA cell cohorts, SBSPON RNA expression is significantly associated with the go_rna of many other GO terms, with 1,675 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SBSPON-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Intracellular pH reduction, and Regulation of intracellular transport. Each is linked with SBSPON in more than 7 cancer types. Because this analysis shows association rather than direction, both SBSPON-to-partner and partner-to-SBSPON results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by SBSPON-low versus SBSPON-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSPON→partner) and Y-score (partner→SBSPON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.067	+0.229	<.001	.006	2	8
CNS	Intracellular pH reduction →	+0.105	+0.949	<.001	<.001	3	7
LUNG_SCLC	Regulation of intracellular transport →	+0.049	+0.786	<.001	.002	3	7
BREAST	Regulation of maintenance of sister chromatid cohesion →	+0.077	+1.171	<.001	.007	3	7
BREAST	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.077	+1.171	<.001	.007	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.137	+0.454	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,675 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by SBSPON expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →