Across TCGA patient cohorts, SBSN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,756 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SBSN-associated proteins across cancer lineages are RAP2B, IVL, and KRT16. Each is linked with SBSN in more than 4 cancer types. Because this analysis shows association rather than direction, both SBSN-to-partner and partner-to-SBSN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSN→partner) and Y-score (partner→SBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAP2B →	+0.465	+1.634	<.001	.008	3	5
UCEC	IVL →	+2.119	+1.470	<.001	<.001	3	5
LSCC	KRT16 →	+1.618	+2.712	<.001	<.001	3	5
HNSC	MEMO1 →	+0.450	+2.518	<.001	<.001	3	5
OV	CGGBP1 →	-0.388	-0.711	<.001	.001	3	4
HNSC	EIF4A1 →	+0.318	+1.692	.008	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,756 associations by consensus.

Exploration

SBSN survival (RNA) · tumor vs normal (RNA) · all SBSN data types