Across TCGA patient cohorts, SBSN protein abundance is significantly associated with the RNA expression of many other genes, with 12,250 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SBSN-associated genes across cancer lineages are ENDOU, RHCG, and S100A8. Each is linked with SBSN in more than 3 cancer types. Because this analysis shows association rather than direction, both SBSN-to-partner and partner-to-SBSN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSN→partner) and Y-score (partner→SBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ENDOU →	+1.597	+1.136	<.001	.003	3	4
LSCC	RHCG →	+2.380	+1.215	<.001	<.001	3	4
HNSC	S100A8 →	+2.235	+1.095	<.001	<.001	3	4
UCEC	IVL →	+2.510	+1.396	<.001	<.001	3	4
HNSC	S100A7A →	+2.406	+1.104	<.001	<.001	3	4
LSCC	KRT6A →	+2.239	+1.244	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,250 associations by consensus.

Exploration

SBSN survival (RNA) · tumor vs normal (RNA) · all SBSN data types