Across TCGA patient cohorts, SBSN mutation is significantly associated with the RNA expression of many other genes, with 1,957 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SBSN-associated genes across cancer lineages are RNU6-879P, OR9Q2, and ACYP1. Each is linked with SBSN in more than 2 cancer types. Because this analysis shows association rather than direction, both SBSN-to-partner and partner-to-SBSN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSN→partner) and Y-score (partner→SBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-879P →	+0.362	+2.292	.002	<.001	3	3
SKCM	OR9Q2 →	+0.025	+4.186	<.001	.007	3	3
UCEC	ACYP1 →	+0.503	+2.523	.001	.001	3	3
UCEC	ZCCHC9 →	+0.455	+2.513	.002	.001	3	3
UCEC	DNAJC7 →	+0.574	+3.169	<.001	<.001	3	3
UCEC	BNIP3P4 →	+0.059	+2.484	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,957 associations by consensus.

Exploration

SBSN survival (RNA) · tumor vs normal (RNA) · all SBSN data types