Across TCGA cell cohorts, SBSN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,566 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SBSN-associated GO terms across cancer lineages are Regulation of intrinsic apoptotic signaling pathway, Regulation of apoptotic signaling pathway, and Negative regulation of apoptotic signaling pathway. Each is linked with SBSN in more than 10 cancer types. Because this analysis shows association rather than direction, both SBSN-to-partner and partner-to-SBSN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSN→partner) and Y-score (partner→SBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of intrinsic apoptotic signaling pathway →	+0.073	+0.829	<.001	.004	3	11
OESOPHAGUS	Regulation of apoptotic signaling pathway →	+0.077	+2.543	.005	.004	3	10
BONE	Negative regulation of apoptotic signaling pathway →	+0.061	+1.443	<.001	.002	3	10
LARGE_INTESTINE	Negative regulation of intrinsic apoptotic signaling pathway →	+0.054	+0.420	<.001	.009	3	9
BONE	Maintenance of protein localization in organelle →	+0.140	+2.519	.001	.001	3	9
BONE	Viral process →	+0.115	+2.607	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,566 associations by consensus.

Exploration

SBSN survival (RNA) · tumor vs normal (RNA) · all SBSN data types