SBNO1

Across TCGA pan-cancer cohorts, SBNO1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SBNO1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SBNO1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SBNO1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where SBNO1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.980	0.899	.006	36	view →
HNSC	DFS	Median	All	0.234	0.895	<.001	24	view →
CCRCC	DFS	Median	III,IV	0.550	0.878	.004	20	view →
PDAC	OS	Quartile	II,III,IV	0.560	0.340	.005	18	view →
UCEC	DFS	Quartile	III,IV	1.000	0.279	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SBNO1–LSCC (DFS)

Open the LSCC breakdown →