SBNO1

Across TCGA patient cohorts, SBNO1 mutation is significantly associated with the RNA expression of many other genes, with 6,063 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SBNO1-associated genes across cancer lineages are MIR7975, RNA5SP271, and LINC01022. Each is linked with SBNO1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SBNO1-to-partner and partner-to-SBNO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7975 grouped by SBNO1-low versus SBNO1-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBNO1→partner) and Y-score (partner→SBNO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MIR7975 →	+0.577	+4.857	<.001	.005	3	3
BRCA	RNA5SP271 →	+0.359	+4.148	<.001	.002	3	3
GBM	LINC01022 →	+0.222	+4.754	<.001	.003	3	3
UCEC	MRPL44 →	+0.505	+1.807	<.001	<.001	3	3
UCEC	COX15 →	+0.539	+2.321	<.001	<.001	3	3
UCEC	DFFB →	+0.557	+2.747	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,063 associations by consensus.

MIR7975 by SBNO1 expression — GBM

Explore this box plot interactively →