SBNO1

Across TCGA patient cohorts, SBNO1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SBNO1-associated genes across cancer lineages are ASNS, Di-Ras3, and PRDX1. Each is linked with SBNO1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SBNO1-to-partner and partner-to-SBNO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by SBNO1-low versus SBNO1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBNO1→partner) and Y-score (partner→SBNO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.496	+1.882	.002	.031	3	3
COAD	Di-Ras3 →	-0.181	-2.576	.026	.011	3	3
UCEC	PRDX1 →	+0.154	+1.415	.019	.043	3	3
UCEC	C-Raf →	+0.112	+1.502	.014	.027	3	3
UCEC	Cyclin-E2 →	+0.140	+1.523	.009	.008	3	3
COAD	GAPDH →	+0.465	+1.882	.028	.031	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

ASNS by SBNO1 expression — COAD

Explore this box plot interactively →