SBNO1

Across TCGA cell cohorts, SBNO1 mutation is significantly associated with the RNA expression of many other genes, with 1,575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SBNO1-associated genes across cancer lineages are ATE1, SLC25A11, and TTC19. Each is linked with SBNO1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SBNO1-to-partner and partner-to-SBNO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATE1 grouped by SBNO1-low versus SBNO1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBNO1→partner) and Y-score (partner→SBNO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ATE1 →	+0.475	+1.850	.004	.006	3	3
LARGE_INTESTINE	SLC25A11 →	+0.463	+3.321	.007	.003	3	3
LARGE_INTESTINE	TTC19 →	+0.913	+2.364	<.001	<.001	3	3
LUNG_NSCLC_LUAD	INO80D →	+0.356	+3.111	.002	.009	3	3
LARGE_INTESTINE	COX15 →	+0.496	+3.043	<.001	<.001	2	4
LARGE_INTESTINE	CCDC138 →	+0.591	+2.364	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,575 associations by consensus.

ATE1 by SBNO1 expression — LARGE_INTESTINE

Explore this box plot interactively →