SBK3

Across TCGA patient cohorts, SBK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SBK3-associated GO terms across cancer lineages are Regulation of substrate adhesion-dependent cell spreading, Regulation of cell-substrate adhesion, and Positive regulation of protein binding. Each is linked with SBK3 in more than 28 cancer types. Because this analysis shows association rather than direction, both SBK3-to-partner and partner-to-SBK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of substrate adhesion-dependent cell spreading grouped by SBK3-low versus SBK3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SBK3→partner) and Y-score (partner→SBK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of substrate adhesion-dependent cell spreading →	+0.074	+0.324	<.001	<.001	3	29
SCLC	Regulation of cell-substrate adhesion →	+0.068	+0.466	.001	.006	2	27
SCLC	Positive regulation of protein binding →	+0.109	+0.608	<.001	<.001	2	27
STAD	Regulation of small GTPase mediated signal transduction →	+0.056	+0.264	<.001	.003	2	27
SCLC	Cell-substrate junction organization →	+0.097	+0.733	<.001	<.001	3	26
SCLC	Fibroblast migration →	+0.099	+0.570	.001	.004	2	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Regulation of substrate adhesion-dependent cell spreading by SBK3 expression — STAD

Explore this box plot interactively →