Across TCGA patient cohorts, SBK1 protein abundance is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SBK1-associated genes across cancer lineages are HEATR3, XAGE3, and KCNA4. Each is linked with SBK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SBK1-to-partner and partner-to-SBK1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBK1→partner) and Y-score (partner→SBK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HEATR3 →	-0.945	-0.703	.002	.006	3	1
BRCA	XAGE3 →	+0.253	+0.721	.005	.006	3	1
BRCA	KCNA4 →	+0.083	+0.783	<.001	.005	3	1
BRCA	SPAG16-DT →	+0.256	+0.639	.002	.003	3	1
BRCA	BOLA3P3 →	+0.976	+0.721	.002	.006	3	1
BRCA	FAM177A1P1 →	+0.300	+0.721	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

SBK1 survival (RNA) · tumor vs normal (RNA) · all SBK1 data types