SBF1

Across TCGA cell cohorts, SBF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,931 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SBF1-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of T-helper 17 cell lineage commitment, and Cytosolic transport. Each is linked with SBF1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SBF1-to-partner and partner-to-SBF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by SBF1-low versus SBF1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SBF1→partner) and Y-score (partner→SBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.155	+0.730	<.001	<.001	3	15
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.245	+0.681	.001	.003	2	15
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.086	+1.055	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.072	+0.739	<.001	<.001	3	13
SOFT_TISSUE	Nuclear export →	+0.094	+1.049	<.001	<.001	3	13
LUNG_SCLC	Symbiont-mediated disruption of host cellular anatomical structure →	+0.127	+0.584	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,931 associations by consensus.

Negative regulation of chromosome condensation by SBF1 expression — SOFT_TISSUE

Explore this box plot interactively →