SBDS

Across TCGA cell cohorts, SBDS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,701 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SBDS-associated GO terms across cancer lineages are Cytosolic ribosome assembly, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, and Base-excision repair, gap-filling. Each is linked with SBDS in more than 18 cancer types. Because this analysis shows association rather than direction, both SBDS-to-partner and partner-to-SBDS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic ribosome assembly grouped by SBDS-low versus SBDS-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SBDS→partner) and Y-score (partner→SBDS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cytosolic ribosome assembly →	+0.110	+0.906	.001	<.001	3	19
OESOPHAGUS	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.158	+1.178	<.001	.001	3	9
BONE	Base-excision repair, gap-filling →	-0.160	-1.465	<.001	<.001	3	9
BONE	Negative regulation of mRNA catabolic process →	-0.051	-0.968	<.001	<.001	3	9
LIVER	Phosphatidylinositol dephosphorylation →	+0.100	+0.692	<.001	<.001	3	8
OESOPHAGUS	Peptidyl-glutamic acid carboxylation →	+0.117	+1.061	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,701 associations by consensus.

Cytosolic ribosome assembly by SBDS expression — KIDNEY

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