SAYSD1

Across TCGA patient cohorts, SAYSD1 mutation is significantly associated with the RNA expression of many other genes, with 1,475 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAYSD1-associated genes across cancer lineages are LINC02348, RNU6-1155P, and RNU6-36P. Each is linked with SAYSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAYSD1-to-partner and partner-to-SAYSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02348 grouped by SAYSD1-low versus SAYSD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAYSD1→partner) and Y-score (partner→SAYSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02348 →	+0.568	+2.778	<.001	<.001	3	2
UCEC	RNU6-1155P →	+0.113	+4.360	.003	.004	3	2
UCEC	RNU6-36P →	+0.489	+2.994	.001	<.001	3	2
SKCM	LINC02489 →	+0.194	+4.695	<.001	.003	3	1
SKCM	OR8X1P →	+0.048	+5.080	.004	.004	3	1
SKCM	EXOGP1 →	+0.041	+5.797	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,475 associations by consensus.

LINC02348 by SAYSD1 expression — UCEC

Explore this box plot interactively →