SAYSD1

Across TCGA cell cohorts, SAYSD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,525 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAYSD1-associated GO terms across cancer lineages are Regulation of DNA-templated transcription initiation, Mitotic cytokinesis, and Vacuole organization. Each is linked with SAYSD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SAYSD1-to-partner and partner-to-SAYSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription initiation grouped by SAYSD1-low versus SAYSD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAYSD1→partner) and Y-score (partner→SAYSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated transcription initiation →	+0.061	+0.667	<.001	<.001	3	12
BREAST	Mitotic cytokinesis →	+0.077	+0.936	.002	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.055	+0.642	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-templated transcription initiation →	+0.074	+0.739	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.057	+0.540	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.095	+0.617	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,525 associations by consensus.

Regulation of DNA-templated transcription initiation by SAYSD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →