Across TCGA patient cohorts, SAXO2 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAXO2-associated genes across cancer lineages are FoxM1, MSH2, and PKC-delta_pS664. Each is linked with SAXO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAXO2-to-partner and partner-to-SAXO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAXO2→partner) and Y-score (partner→SAXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.232	+1.874	.012	.049	3	2
UCEC	MSH2 →	-0.230	-1.674	.005	.040	3	2
UCEC	PKC-delta_pS664 →	-0.108	-3.700	.012	.001	3	2
UCEC	TFRC →	+0.469	+2.321	.014	.033	3	2
UCEC	ASNS →	+0.451	+2.222	<.001	.010	3	2
UCEC	ATM →	-0.507	-2.222	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

SAXO2 survival (RNA) · tumor vs normal (RNA) · all SAXO2 data types