Across TCGA cell cohorts, SAXO2 mutation is significantly associated with the mutation status of many other genes, with 196 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAXO2-associated genes across cancer lineages are ALDH1A3, BEND4, and RBBP4. Each is linked with SAXO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAXO2-to-partner and partner-to-SAXO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAXO2→partner) and Y-score (partner→SAXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ALDH1A3 →	+6.044	+6.044	.001	.001	1	2
STOMACH	BEND4 →	+4.807	+4.807	.008	.008	1	2
SKIN	RBBP4 →	+4.824	+5.392	.004	.004	1	2
SKIN	ARSK →	+4.239	+5.053	.007	.007	1	2
SKIN	TOR1AIP2 →	+4.824	+5.392	.004	.004	1	2
LARGE_INTESTINE	SOWAHD →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 196 associations by consensus.

Exploration

SAXO2 survival (RNA) · tumor vs normal (RNA) · all SAXO2 data types