SAXO1

Across TCGA cell cohorts, SAXO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,637 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAXO1-associated GO terms across cancer lineages are Positive regulation of stress fiber assembly, Negative regulation of autophagosome assembly, and Interleukin-10-mediated signaling pathway. Each is linked with SAXO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SAXO1-to-partner and partner-to-SAXO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stress fiber assembly grouped by SAXO1-low versus SAXO1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAXO1→partner) and Y-score (partner→SAXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of stress fiber assembly →	+0.087	+0.103	.001	.001	3	5
LARGE_INTESTINE	Negative regulation of autophagosome assembly →	+0.072	+0.034	.002	.007	2	6
SOFT_TISSUE	Interleukin-10-mediated signaling pathway →	+0.165	+0.103	<.001	.001	3	5
SKIN	Positive regulation of supramolecular fiber organization →	+0.038	+0.017	.006	.007	2	6
SKIN	Golgi to plasma membrane transport →	+0.054	+0.017	<.001	<.001	3	5
SKIN	Positive regulation of canonical Wnt signaling pathway →	+0.046	+0.021	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,637 associations by consensus.

Positive regulation of stress fiber assembly by SAXO1 expression — SOFT_TISSUE

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