SATL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SATL1 mutation is significantly associated with the RNA expression of many other genes, with 3,714 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SATL1-associated genes across cancer lineages are RNU6-1064P, C11orf49, and LAMTOR1. Each is linked with SATL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SATL1-to-partner and partner-to-SATL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATL1→partner) and Y-score (partner→SATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-1064P →+0.787+5.321<.001.00133
UCECC11orf49 →+0.334+1.949.003.00832
LUSCLAMTOR1 →+0.422+3.459.005.00532
UCECADAM33 →-0.780-4.034.001<.00132
UCECMARVELD2 →+0.395+2.243.009.00532
UCECPDZK1IP1 →-1.532-1.847<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,714 associations by consensus.

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