SATL1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SATL1 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SATL1-associated genes across cancer lineages are HER3_pY1289, mTOR_pS2448, and Smad3. Each is linked with SATL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SATL1-to-partner and partner-to-SATL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATL1→partner) and Y-score (partner→SATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHER3_pY1289 →+0.074+1.874.012.04932
UCECmTOR_pS2448 →-0.130-2.102.010.01632
UCECSmad3 →+0.122+1.807.017.02532
UCECDJ-1 →+0.112+3.335.049.00532
UCECEGFR_pY1068 →-0.259-2.523.002<.00131
UCECeIF4E →+0.192+3.598.007.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

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