Across TCGA cell cohorts, SATL1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SATL1-associated genes across cancer lineages are CT45A2, OR4F21, and STRA8. Each is linked with SATL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SATL1-to-partner and partner-to-SATL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATL1→partner) and Y-score (partner→SATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CT45A2 →	+1.326	+4.137	<.001	.001	3	1
LARGE_INTESTINE	OR4F21 →	+0.187	+3.878	<.001	.003	3	1
BREAST	STRA8 →	+0.193	+3.691	.009	.009	3	1
BREAST	SPATA48 →	+0.124	+4.196	<.001	.006	3	1
BLOOD_Leukemia	MCHR2 →	+0.046	+5.539	<.001	.003	3	1
BLOOD_Leukemia	C14orf177 →	+0.076	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

SATL1 survival (RNA) · tumor vs normal (RNA) · all SATL1 data types