SATB2

Across TCGA patient cohorts, SATB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,016 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SATB2-associated proteins across cancer lineages are SATB2_S39, SEPTIN11, and ICAM1. Each is linked with SATB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SATB2-to-partner and partner-to-SATB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SATB2 versus SATB2_S39 in LSCC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB2→partner) and Y-score (partner→SATB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SATB2_S39 →	+1.109	+1.350	<.001	<.001	3	5
BRCA	SEPTIN11 →	+0.413	+0.541	<.001	.001	3	5
CCRCC	ICAM1 →	-0.405	-0.546	.003	.001	3	4
GBM	ARHGAP30 →	-0.507	-0.736	.001	.002	3	4
LSCC	THEMIS2 →	-0.370	-0.458	<.001	<.001	3	4
PDAC	FSCN1_S39 →	+0.601	+0.472	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,016 associations by consensus.

SATB2 vs SATB2_S39 — LSCC

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