SATB2

Across TCGA patient cohorts, SATB2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,985 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SATB2-associated genes across cancer lineages are PLCB4, TFR2, and CCND2. Each is linked with SATB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SATB2-to-partner and partner-to-SATB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SATB2 versus PLCB4 in COAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB2→partner) and Y-score (partner→SATB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PLCB4 →	+1.530	+0.710	<.001	<.001	3	2
BRCA	TFR2 →	-0.830	-0.610	<.001	.003	3	2
GBM	CCND2 →	+0.993	+0.500	<.001	<.001	3	2
COAD	CKMT2 →	+1.286	+0.470	<.001	<.001	3	2
BRCA	PTPRG →	+0.769	+0.773	.001	.001	3	2
BRCA	CRELD2 →	-0.796	-0.985	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,985 associations by consensus.

SATB2 vs PLCB4 — COAD

Explore this scatter interactively →