SATB2

Across TCGA cell cohorts, SATB2 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SATB2-associated genes across cancer lineages are OR10K1, TAS2R39, and IL4. Each is linked with SATB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SATB2-to-partner and partner-to-SATB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K1 grouped by SATB2-low versus SATB2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB2→partner) and Y-score (partner→SATB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10K1 →	+0.485	+3.556	<.001	.001	3	2
BLOOD_Leukemia	TAS2R39 →	+0.039	+3.661	.003	.001	3	2
BLOOD_Leukemia	IL4 →	+2.733	+3.007	<.001	.007	3	1
BLOOD_Leukemia	IL22 →	+0.021	+4.247	<.001	.004	3	1
BLOOD_Leukemia	LRRIQ1 →	+0.285	+3.409	<.001	.008	3	1
BLOOD_Leukemia	GCM1 →	+0.174	+3.483	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

OR10K1 by SATB2 expression — BLOOD_Leukemia

Explore this box plot interactively →