Across TCGA patient cohorts, SATB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SATB1-associated proteins across cancer lineages are PPP1R12B, AIMP2, and SPINT1. Each is linked with SATB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SATB1-to-partner and partner-to-SATB1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB1→partner) and Y-score (partner→SATB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPP1R12B →	+0.719	+0.599	<.001	<.001	3	5
OV	AIMP2 →	-0.164	-0.714	<.001	.001	3	5
CCRCC	SPINT1 →	-0.422	-0.465	.002	<.001	3	4
GBM	BRD3 →	+0.320	+0.538	<.001	<.001	3	4
BRCA	SATB1_S38 →	+1.034	+0.824	<.001	<.001	3	4
GBM	SETMAR →	+0.413	+0.648	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,034 associations by consensus.

Exploration

SATB1 survival (RNA) · tumor vs normal (RNA) · all SATB1 data types